Decreased Microvascular Nitric Oxide–Dependent Vasodilation in Postural Tachycardia Syndrome
نویسندگان
چکیده
منابع مشابه
Decreased microvascular nitric oxide-dependent vasodilation in postural tachycardia syndrome.
BACKGROUND One variant of postural tachycardia syndrome (POTS), designated low-flow POTS, is associated with decreased peripheral blood flow related to impaired local vascular regulation. METHODS AND RESULTS To investigate the hypothesis that microvascular endothelial dysfunction produces decreased peripheral blood flow in low-flow POTS, we performed experiments using laser-Doppler flowmetry ...
متن کاملMicrovascular filtration is increased in postural tachycardia syndrome.
BACKGROUND Postural tachycardia syndrome (POTS) is related to defective peripheral vasoconstriction of dependent extremities with redistributive hypovolemia. METHODS AND RESULTS To test whether enhanced microvascular filtration produces leg enlargement, we studied 12 patients 13 to 19 years of age with POTS and defective leg vasoconstriction and 13 age-matched healthy control subjects, with s...
متن کاملCutaneous neuronal nitric oxide is specifically decreased in postural tachycardia syndrome.
Low flow postural tachycardia syndrome (POTS), is associated with reduced nitric oxide (NO) activity assumed to be of endothelial origin. We tested the hypothesis that cutaneous microvascular neuronal NO (nNO) is impaired, rather than endothelial NO (eNO), in POTS. We performed three sets of experiments on subjects aged 22.5 +/- 2 yr. We used laser-Doppler flowmetry response to sequentially inc...
متن کاملPostural tachycardia syndrome (POTS).
INTRODUCTION POTS is defined as the development of orthostatic symptoms associated with a heart rate (HR) increment >or=30, usually to >or=120 bpm without orthostatic hypotension. Symptoms of orthostatic intolerance are those due to brain hypoperfusion and those due to sympathetic overaction. METHODS We provide a review of POTS based primarily on work from the Mayo Clinic. RESULTS Females p...
متن کاملPostural tachycardia syndrome (POTS).
Postural Tachycardia Syndrome (POTS) Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2013 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation doi: 10.1161/CIRCULATIONAHA.112.144501 2013;127:2336-2342 Circulation. http://circ.ahajournals.org/content/127/23/2336 World Wide Web at: The ...
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ژورنال
عنوان ژورنال: Circulation
سال: 2005
ISSN: 0009-7322,1524-4539
DOI: 10.1161/circulationaha.104.526764